Clonidine Dosage – What You Need to Know

If you’ve been prescribed clonidine, the biggest question is probably "how much should I take?" Whether you’re using it for high blood pressure, ADHD, or opioid withdrawal, the dose can vary a lot. Below we break down the common dosing ranges, how doctors decide on the right amount, and what to watch out for when you start or change your dose.

Dosing Basics for Different Uses

For high blood pressure, most adults begin with 0.1 mg taken twice a day. Your doctor may raise the dose by 0.1 mg every week until your blood pressure is under control, but they rarely go above 0.6 mg total per day.

If you’re treating ADHD, the starting point is usually the same – 0.1 mg once or twice daily. Kids and teens often stay in the 0.1‑0.4 mg range, split into two doses. Some adults need a bit more, but anyone going above 0.5 mg should be monitored closely for side effects.

When clonidine is used to ease opioid withdrawal, doctors often start at 0.3 mg every 6‑8 hours. After the first couple of days the dose is tapered down gradually, sometimes over a week or two, depending on how you feel.

For children under 12 who need clonidine for ADHD or hypertension, the dose is usually calculated by weight – about 1 µg per kilogram of body weight, given twice daily. Pediatric dosing always starts low and goes up slowly.

How to Adjust and Take Your Dose Safely

When you first start clonidine, your doctor will likely keep the dose low to see how you react. If blood pressure stays high or ADHD symptoms don’t improve after a week, they may increase it by 0.1 mg. The key is not to jump too quickly – sudden jumps can cause dizziness, dry mouth, or a fast heartbeat.

Elderly patients often need a lower starting dose (sometimes just 0.05 mg twice daily) because their bodies process the drug slower. If you have kidney or liver problems, your doctor might also keep the dose on the low side and check your labs more often.

Missing a dose? Take it as soon as you remember unless it’s almost time for your next one. In that case just skip the missed pill – don’t double up. Doubling can cause a sudden drop in blood pressure, which feels like light‑headedness or fainting.

Store clonidine at room temperature, away from moisture and heat. Keep it out of reach of kids – even a tiny amount can be dangerous for a child.

Common side effects include dry mouth, drowsiness, constipation, and a feeling of cold hands or feet. Most people notice these in the first few days and they get better as your body adjusts. If you feel severe dizziness, fainting, or a rapid heartbeat, call your doctor right away.

Remember that clonidine works best when you take it exactly as prescribed. Skipping doses, changing timing, or stopping suddenly can cause a rebound rise in blood pressure, which can be risky.

In short, start low, go slow, and keep an eye on how you feel. Talk to your doctor about any side effects, and never adjust the dose on your own. With the right plan, clonidine can help control blood pressure, improve focus, or ease withdrawal safely.